Nondisjunction of the sex chromosomes during gametogenesis

• Superfemale (XXX)

2nd frequent disorder (90 % maternal nondisjunction)

44 XX _ 22 XX _ 44 XXX _ 22 X

• YO (lethal) - fetus dies in utero

44 XX _ 22 0 _ 44 Y0 _ 22 Y

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